Hydroxychloroquine: Trump's Covid-19 'cure' increases deaths, global study

Hydroxychloroquine, the anti-malarial drug Donald Trump is taking to prevent Covid-19, has increased deaths in patients treated with it in hospitals around the world, a study has shown.The biggest increase was in the group treated with hydroxychloroquine in combination with an antibiotic, where 8% of patients developed a heart arrhythmia compared with 0.3% of patients not given the drugs.“Whilst controlled trials will be required for confident affirmation, the indications are that these drugs certainly ought not to be used outside of a trial setting where patients can be monitored for complications. One might also question whether the resources necessary for large studies might be better diverted to other causes, at the same time allowing the drugs themselves to be used for their original purpose.Stephen Evans, professor of pharmacoepidemiology at the London School of Hygiene and Tropical Medicine, said it was unlikely that trials would now find any substantial benefit from the drugs. “A definitive answer still awaits the results of the randomised trials, but it is clear that the drugs should not be given for treatment of Covid-19 other than in the context of a randomised trial.“It might even be said that to go on giving them, other than in a trial, is unethical, given this evidence that is not yet contradicted by other available evidence.”

Read more at: https://www.theguardian.com/science/2020/may/22/hydroxychloroquine-trumps-covid-19-cure-increases-deaths-global-study-finds